Genetics and the causes of ankylosing spondylitis
Hanson, Aimee & Brown, Matt (2017) Genetics and the causes of ankylosing spondylitis. Rheumatic Disease Clinics of North America, 43(3), pp. 401-414.
Description
Ankylosing spondylitis (AS) is a common inflammatory arthritis in which genetic factors are the primary determinants of disease risk and severity. Substantial progress has been made in identifying genetic pathways involved in the disease, and in translating those discoveries to drug discovery programs. Recently discovered novel disease pathways include those involved in control of DNA methylation, bacterial sensing, and mucosal immunity. Additional pathways are likely to be identified as a higher proportion of the genetic risk of AS is determined.
Impact and interest:
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| ID Code: | 117536 | ||
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| Item Type: | Contribution to Journal (Journal Article) | ||
| Refereed: | Yes | ||
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| Measurements or Duration: | 14 pages | ||
| DOI: | 10.1016/j.rdc.2017.04.006 | ||
| ISSN: | 0889-857X | ||
| Pure ID: | 33264432 | ||
| Divisions: | Past > QUT Faculties & Divisions > Faculty of Health Past > Institutes > Institute of Health and Biomedical Innovation |
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| Copyright Owner: | Consult author(s) regarding copyright matters | ||
| Copyright Statement: | This work is covered by copyright. Unless the document is being made available under a Creative Commons Licence, you must assume that re-use is limited to personal use and that permission from the copyright owner must be obtained for all other uses. If the document is available under a Creative Commons License (or other specified license) then refer to the Licence for details of permitted re-use. It is a condition of access that users recognise and abide by the legal requirements associated with these rights. If you believe that this work infringes copyright please provide details by email to qut.copyright@qut.edu.au | ||
| Deposited On: | 13 Apr 2018 11:55 | ||
| Last Modified: | 24 Dec 2025 20:23 |
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