Anti-viral response of bronchial epithelial cells in adults with chronic obstructive pulmonary disease (COPD)
Description
This project was an investigation of the antiviral response of lung cells from people with chronic obstructive pulmonary disease (COPD). A novel 3D culture method was used to mimic a real-life airway epithelium. By using this model we found that COPD results in a switch in the type of interferon the cells produce, which has an effect on the antiviral response and will inform the use of interferon as a treatment.
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| ID Code: | 118571 |
|---|---|
| Item Type: | QUT Thesis (Masters by Research) |
| Supervisor: | Spann, Kirsten, Walsh, Terry, & Beagley, Kenneth |
| Keywords: | apoptosis, bronchial epithelial cells, chronic obstructive pulmonary disease, human metapneumovirus, respiratory syncytial virus, interferon, virus exacerbations |
| DOI: | 10.5204/thesis.eprints.118571 |
| Divisions: | Past > QUT Faculties & Divisions > Faculty of Health Current > Schools > School of Biomedical Sciences |
| Institution: | Queensland University of Technology |
| Deposited On: | 11 Jun 2018 00:57 |
| Last Modified: | 11 Jun 2018 00:57 |
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