Quantitative characterization of paediatric burn blister fluid
Zang, Tuo (2018) Quantitative characterization of paediatric burn blister fluid. PhD by Publication, Queensland University of Technology.
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Tuo Zang Thesis
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Available under License Creative Commons Attribution Non-commercial No Derivatives 4.0. |
Description
Burn injury is a highly traumatic event for any infant or child. The degree of burn severity often determine the treatment operations and the extent of later scar formation, which may require long-term surgical remediation or skin grafting. This investigation quantitatively characterises the biochemical composition of burn blister fluid from paediatric patients using advanced analytical techniques. The correlation of the abundance of proteins and metabolic molecules were explored by statistical and bioinformatics methods. Thus, this study is able to provide a timely and objective measurement that may reflect the burn wound microenvironment and assist clinical diagnosis.
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| ID Code: | 122968 |
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| Item Type: | QUT Thesis (PhD by Publication) |
| Supervisor: | Parker, Tony, Cuttle, Leila, Wellard, Mark, & Broszczak, Daniel |
| Additional Information: | The Faculty has granted an embargo until 14th November 2020. |
| Keywords: | Burn injury, Blister fluid, Proteomics, Metabolomics, Bioinformatics, Liquid chromatography tandem mass spectrometry, Proton nuclear magnetic resonance spectroscopy, SWATH, Clinical diagnosis, Biomarker discovery |
| DOI: | 10.5204/thesis.eprints.122968 |
| Divisions: | Past > QUT Faculties & Divisions > Faculty of Health Current > Schools > School of Biomedical Sciences |
| Institution: | Queensland University of Technology |
| Deposited On: | 26 Nov 2018 02:57 |
| Last Modified: | 18 Jan 2025 14:43 |
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