A hybrid CA-PDE Model of chlamydia trachomatis infection in the female genital tract
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Description
Chlamydia trachomatis is amongst the most common sexually transmitted diseases in the world and when left untreated, may lead to serious sequelae particularly in women such as pelvic inflammatory disease, ectopic pregnancy and infertility. Currently, most mathematical modelling in the literature regarding Chlamydia is based on time dependent differential equations. The serious pathology associated with C. trachomatis occurs when the chlamydial infection ascends to the upper genital tract. But no modelling study has investigated the important spatial aspects of the disease. In this work, we include spatiotemporal considerations of the progression of chlamydial infection in the genital tract. This novel direction is achieved using cellular automata modelling with probabilistic decision processes. In this presentation, the modelling strategy will be described, as well as its relationship with existing models and the advances in understanding that are achieved with such a model. Such an approach provides valuable insights into disease progression and will lead to experimentally testable predictions and a basis for further investigation in this area.
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ID Code: | 12623 | ||
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Item Type: | Contribution to conference (Paper/Presentation) | ||
Refereed: | No | ||
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Keywords: | chlamydia, hybrid CA-PDE model, mathematics | ||
Pure ID: | 57200458 | ||
Divisions: | Past > QUT Faculties & Divisions > Faculty of Science and Technology Past > Institutes > Institute of Health and Biomedical Innovation Past > QUT Faculties & Divisions > Science & Engineering Faculty Current > Research Centres > Australian Research Centre for Aerospace Automation Past > Research Centres > CRC for Diagnostics |
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Copyright Owner: | Copyright 2008 (please consult author) | ||
Copyright Statement: | This work is covered by copyright. Unless the document is being made available under a Creative Commons Licence, you must assume that re-use is limited to personal use and that permission from the copyright owner must be obtained for all other uses. If the document is available under a Creative Commons License (or other specified license) then refer to the Licence for details of permitted re-use. It is a condition of access that users recognise and abide by the legal requirements associated with these rights. If you believe that this work infringes copyright please provide details by email to qut.copyright@qut.edu.au | ||
Deposited On: | 25 Feb 2008 00:00 | ||
Last Modified: | 03 Mar 2024 09:08 |
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