Performance of registration tools on high-resolution 3D brain images
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Description
Recent progress in tissue clearing allows the imaging of entire organs at single-cell resolution. A necessary step in analysing these images is registration across samples. Existing methods of registration were developed for lower resolution image modalities (e.g., MRI) and it is unclear whether their performance and accuracy is satisfactory at this larger scale (several gigabytes for a whole mouse brain). In this study, we evaluated five freely available image registration tools. We used several performance metrics to assess accuracy, and completion time as a measure of efficiency. The results of this evaluation suggest that ANTS provides the best registration accuracy, while Elastix has the highest computational efficiency among the methods with an acceptable accuracy. The results also highlight the need to develop new registration methods optimised for these high-resolution 3D images.
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ID Code: | 129503 | ||||||
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Item Type: | Chapter in Book, Report or Conference volume (Conference contribution) | ||||||
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Measurements or Duration: | 4 pages | ||||||
DOI: | 10.1109/EMBC.2018.8512403 | ||||||
ISBN: | 978-1-5386-3647-3 | ||||||
Pure ID: | 33315511 | ||||||
Divisions: | Past > Institutes > Institute for Future Environments Past > QUT Faculties & Divisions > Science & Engineering Faculty Past > Schools > School of Electrical Engineering & Computer Science |
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Copyright Owner: | Consult author(s) regarding copyright matters | ||||||
Copyright Statement: | This work is covered by copyright. Unless the document is being made available under a Creative Commons Licence, you must assume that re-use is limited to personal use and that permission from the copyright owner must be obtained for all other uses. If the document is available under a Creative Commons License (or other specified license) then refer to the Licence for details of permitted re-use. It is a condition of access that users recognise and abide by the legal requirements associated with these rights. If you believe that this work infringes copyright please provide details by email to qut.copyright@qut.edu.au | ||||||
Deposited On: | 22 May 2019 23:52 | ||||||
Last Modified: | 07 Jul 2024 17:26 |
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