Investigation of cellular and molecular mechanisms involved in contextual fear memory encoding
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Nicholas Chaaya Thesis
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Available under License Creative Commons Attribution Non-commercial No Derivatives 4.0. |
Description
This thesis examined the role of three distinct brain regions following the formation or maintenance of contextual fear memories (e.g. fear memories to particular rooms or environments). The results of this thesis demonstrated how neuronal activity and neuronal plasticity alter following minor changes to the context via addition of simple stimuli, such as auditory tones. This indicates that the manner in which a fear memory is obtained alters where and how it is stored within the brain. This has implications for individuals with fear-based disorders, such as post-traumatic stress disorder.
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| ID Code: | 134258 |
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| Item Type: | QUT Thesis (PhD by Publication) |
| Supervisor: | Bartlett, Selena, Belmer, Arnauld, Battle, Andrew, Yamamoto, Naohide, & Johnson, Luke |
| Keywords: | Post-Traumatic Stress Disorder, Contextual Fear Conditioning, Plasticity, Neuroscience, Microglia, Fear Conditioning, Amygdala, Hippocampus, Prefrontal Cortex, Memory |
| DOI: | 10.5204/thesis.eprints.134258 |
| Divisions: | Past > QUT Faculties & Divisions > Faculty of Health Current > Schools > School of Clinical Sciences |
| Institution: | Queensland University of Technology |
| Deposited On: | 28 Nov 2019 00:51 |
| Last Modified: | 28 Nov 2019 00:51 |
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