The Stability of Corneal Topography in the Post-Blink Interval

Buehren, Tobias F., Collins, Michael J., Iskander, D. Robert, Davis, Brett A., & Lingelbach, Bernd (2001) The Stability of Corneal Topography in the Post-Blink Interval. Cornea, 20(8), pp. 826-833.


Abstract Only

Purpose. Videokeratoscopes provide a wealth of information about the topography of the ocular surface. Although there have been numerous studies of the accuracy and precision of videokeratoscopes with inanimate test objects, little information exists on their precision (repeatability) for real eyes. Methods. To investigate the stability of the ocular surface in the inter-blink period, 10 patients were recruited for videokeratoscopy. Tear break-up time was measured and videokeratographs were acquired immediately post-blink and again at 4, 8, and 12 seconds post-blink. To permit statistical inferences to be drawn from the data, we acquired 24 videokeratographs for each of the four post-blink intervals. The videokeratograph data were interpolated (bilinear) to a common grid, and average and standard deviation (SD) maps were derived for each post-blink condition. t Tests were used to test the significance of changes observed in the topography. Results. The instantaneous power SD maps showed increasing variation toward the periphery, with most maps showing less than ±0.5 diopters (D) of SD in the central 4 to 5 mm and variation in the periphery often reaching more than ±1 D SD at the edge of an 8-mm diameter. When the 4-, 8-, and 12-second average maps were subtracted from the average map acquired immediately after blinking, regions of statistically significant (p < 0.001) change were apparent in the upper and lower regions of the maps. The upper and lower bands of change were found to correlate with the natural position of the patients’ lid margins. Conclusions. For normal eyes, the central regions of videokeratographs show high stability in the inter-blink period. However, the upper and lower edges of 8-mm diameter maps show statistically significant variability, which appears to be related to the effects of eyelid pressure.

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54 citations in Web of Science®
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ID Code: 1461
Item Type: Journal Article
Refereed: Yes
Additional Information: Self-archiving of the author-version is not yet supported by this publisher. For more information, please refer to the journal’s website (see link) or contact the author. Author contact details,.au (Tobias Buehren)
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ISSN: 1536-4798
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2001 Lippincott, Williams & Wilkins
Deposited On: 10 Jan 2006 00:00
Last Modified: 19 May 2010 15:55

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