Genome sequencing in esophageal squamous cell carcinoma
Description
Technological advances in the form of next-generation sequencing allow sequencing of large numbers of different DNA sequences in a single/parallel reaction compared to conventional sequencing. It is a powerful tool which has enabled comprehensive characterization of esophageal squamous cell carcinoma. Whole-genome sequencing is the most comprehensive but expensive, whereas whole-exome sequencing is cost-effective, but it only works for the known genes. Thus, second-generation sequencing methods can provide a complete picture of the esophageal squamous cell carcinoma genome by detecting and discovering different type of alterations in the cancer which may lead to the development of effective diagnostic and therapeutic approaches for esophageal squamous cell carcinoma.
Impact and interest:
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| ID Code: | 198328 | ||
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| Item Type: | Chapter in Book, Report or Conference volume (Chapter) | ||
| Series Name: | Methods in Molecular Biology | ||
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| Measurements or Duration: | 24 pages | ||
| Keywords: | Esophageal squamous cell carcinoma, Next-generation sequencing | ||
| DOI: | 10.1007/978-1-0716-0377-2_17 | ||
| ISBN: | 978-1-0716-0376-5 | ||
| Pure ID: | 49331987 | ||
| Divisions: | Current > Research Centres > Centre for Genomics and Personalised Health Past > Institutes > Institute of Health and Biomedical Innovation Current > QUT Faculties and Divisions > Faculty of Health |
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| Copyright Owner: | Springer Science+Business Media, LLC, part of Springer Nature 2020 | ||
| Copyright Statement: | This work is covered by copyright. Unless the document is being made available under a Creative Commons Licence, you must assume that re-use is limited to personal use and that permission from the copyright owner must be obtained for all other uses. If the document is available under a Creative Commons License (or other specified license) then refer to the Licence for details of permitted re-use. It is a condition of access that users recognise and abide by the legal requirements associated with these rights. If you believe that this work infringes copyright please provide details by email to qut.copyright@qut.edu.au | ||
| Deposited On: | 02 Apr 2020 06:46 | ||
| Last Modified: | 29 Feb 2024 14:57 |
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