Targeting epithelial to mesenchymal transition (EMT) to modulate prostate cancer cell chemoresistance
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Akanksha Upadhyaya Thesis
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Available under License Creative Commons Attribution Non-commercial No Derivatives 4.0. |
Description
Understanding why some cancer cells do not respond to chemotherapy is critical to developing new ways to control cancer. This project defined the important role of tumour cell plasticity in the response of prostate cancer cells to chemotherapy drugs. Key proteins that control cell plasticity have emerged as promising theranostic targets that can be pursued to develop new approaches to improve outcomes for men with metastatic prostate cancer.
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| ID Code: | 201657 |
|---|---|
| Item Type: | QUT Thesis (PhD) |
| Supervisor: | Williams, Elizabeth & Hollier, Brett |
| Keywords: | Prostate Cancer, Chemoresistance, Epithelial to Mesenchymal Transition, Metastasis, Transcription Factors |
| DOI: | 10.5204/thesis.eprints.201657 |
| Divisions: | Past > QUT Faculties & Divisions > Faculty of Health Current > Schools > School of Biomedical Sciences |
| Institution: | Queensland University of Technology |
| Deposited On: | 23 Jul 2020 22:27 |
| Last Modified: | 23 Jul 2020 22:27 |
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