Development of an electrochemical immunosensor for phenylketonuria monitoring
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Andrew Stewart Thesis
(PDF 9MB)
Available under License Creative Commons Attribution Non-commercial No Derivatives 4.0. |
Description
The project explored biosensors to potentially develop a home health monitor for people with phenylketonuria (PKU). The thesis included studies of biochip design and preparation, design of a reader unit and concept design for on-chip reagent handling. The biosensor comprised anti-phenylalanine antibodies assembled on a gold electrode, when exposed to human serum would produce an electrochemical response. The research found strong evidence for the potential health benefits of such a monitor for a variety of individual situations and concluded that enzymatic methods may present the best opportunity for successful commercialisation.
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| ID Code: | 208391 |
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| Item Type: | QUT Thesis (Master of Philosophy) |
| Supervisor: | Kiriakous, Emad, O'Mullane, Anthony, & Ayoko, Godwin |
| Keywords: | Phenylketonuria, Monitor, PKU, Phenylalanine, Health, Immunosensor, Biosensor |
| DOI: | 10.5204/thesis.eprints.208391 |
| Divisions: | Past > QUT Faculties & Divisions > Science & Engineering Faculty Current > Schools > School of Chemistry & Physics |
| Institution: | Queensland University of Technology |
| Deposited On: | 16 Mar 2021 06:59 |
| Last Modified: | 16 Mar 2021 06:59 |
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