Role of the Serotonin 2B Receptor in the Reinforcing Effects of Psychostimulants
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Description
In this chapter, we will review the current literature underlying the essential role played by the 5-HT2B receptor in the regulation of serotonin and dopamine neurotransmission, by first focusing on its involvement in the psychostimulant effects of the club-drug Ecstasy, then by further describing its contribution to the psychostimulant effects of amphetamine, and finally, by presenting its role in the psychostimulant effects of cocaine. Throughout this review, we will compare the current findings in mice and rats with an emphasis on interspecies discrepancies. to conclude, we will discuss the potential pharmacotherapeutic strategies for the treatment of psychostimulant addiction.
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| ID Code: | 210319 | ||||
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| Item Type: | Chapter in Book, Report or Conference volume (Chapter) | ||||
| Series Name: | Receptors | ||||
| ORCID iD: |
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| Measurements or Duration: | 14 pages | ||||
| Keywords: | Amphatamine, Cocaine, MDMA, Mice, Psychostimulant, Rats, Serotonin | ||||
| DOI: | 10.1007/978-3-030-55920-5_18 | ||||
| ISBN: | 978-3-030-55919-9 | ||||
| Pure ID: | 83712281 | ||||
| Divisions: | Current > QUT Faculties and Divisions > Faculty of Health Current > Schools > School of Clinical Sciences Current > Schools > School of Biomedical Sciences |
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| Copyright Owner: | 2021 Springer Nature Switzerland AG | ||||
| Copyright Statement: | This work is covered by copyright. Unless the document is being made available under a Creative Commons Licence, you must assume that re-use is limited to personal use and that permission from the copyright owner must be obtained for all other uses. If the document is available under a Creative Commons License (or other specified license) then refer to the Licence for details of permitted re-use. It is a condition of access that users recognise and abide by the legal requirements associated with these rights. If you believe that this work infringes copyright please provide details by email to qut.copyright@qut.edu.au | ||||
| Deposited On: | 12 May 2021 05:24 | ||||
| Last Modified: | 29 Feb 2024 15:09 |
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