Patient-specific computational biomechanical analysis of carotid atherosclerotic plaques based on MRI
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Jessica Benitez Mendieta Thesis
(PDF 19MB)
Available under License Creative Commons Attribution Non-commercial No Derivatives 4.0. |
Description
This thesis focuses on the biomechanical analysis of carotid atherosclerosis based on medical imaging. The rupture of carotid atherosclerotic plaques is the leading cause of acute cardiovascular events, such as stroke. For this analysis, patient-specific and image-based carotid models were developed for computational analysis to assess factors associated with plaque development and rupture. This study provided further knowledge in areas such as fluid dynamics of carotid arteries with stenosis, the role of the carotid plaque components, and a new technique for structural analysis of carotid plaques. These approaches will help clinicians in the diagnosis and treatment of carotid atherosclerosis.
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| ID Code: | 213840 |
|---|---|
| Item Type: | QUT Thesis (PhD by Publication) |
| Supervisor: | Li, Zhiyong & Fontanarosa, Davide |
| Additional Information: | Recipient of a 2021 Outstanding Doctoral Thesis Award |
| Keywords: | Carotid atherosclerosis, Blood vessels, Computational Fluid dynamics, Structural analysis, Magnetic resonance imaging, Vulnerable plaque, Fluid-structure interaction, Stenosis, ODTA |
| DOI: | 10.5204/thesis.eprints.213840 |
| Divisions: | Current > QUT Faculties and Divisions > Faculty of Engineering Current > Schools > School of Mechanical, Medical & Process Engineering |
| Institution: | Queensland University of Technology |
| Deposited On: | 19 Oct 2021 02:42 |
| Last Modified: | 12 Dec 2022 04:50 |
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