Spatial patterning of hydrogels via 3D covalent transfer stamping from a fugitive ink

, Dalton, Paul, & (2018) Spatial patterning of hydrogels via 3D covalent transfer stamping from a fugitive ink. Macromolecular Rapid Communications, 39(4), Article number: 1700564 1-5.

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Description

In this study, a novel hydrogel patterning approach using 3D covalent transfer stamping from a fugitive ink is introduced. A model transfer molecule (7-diethylamino-3-(4′maleimidylphenyl)-4-methylcoumarin (CPM)) is absorbed into a 3D fugitive ink stamp made from poly(caprolactone), and then encapsulated in a poly(ethylene glycol) hydrogel. As the CPM diffuses from the fugitive ink to the curing hydrogel it is selectively covalently bound at the boundary of the ink and the hydrogel. Removal of the fugitive ink by solvent exchange leads to a negative copy of interconnected channels patterned with the localized transfer of the molecules at the hydrogel interface. The results suggest that small molecules can be patterned in porous hydrogels in a spatially controllable manner and that the transferred amount can be tuned.

Impact and interest:

3 citations in Scopus
5 citations in Web of Science®
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ID Code: 223417
Item Type: Contribution to Journal (Journal Article)
Refereed: Yes
ORCID iD:
Dargaville, Timorcid.org/0000-0003-4665-9508
Additional Information: Acknowledgements: T.R.D. gratefully acknowledges the ARC Future Fellowship scheme (FT150100408) for financial support.
Measurements or Duration: 5 pages
Keywords: Hydrogel, fugitive ink, poly(ethylene glycol), spatial patterning, transfer molecules
DOI: 10.1002/marc.201700564
ISSN: 1521-3927
Pure ID: 33334716
Divisions: Past > Institutes > Institute of Health and Biomedical Innovation
Past > QUT Faculties & Divisions > Science & Engineering Faculty
Funding:
Copyright Owner: 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
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Deposited On: 07 Nov 2021 03:51
Last Modified: 15 May 2026 06:33