T1-based sensing of mammographic density using single-sided portable NMR
Tourell, Monique, Ali, Tonima Sumya, Hugo, Honor, Pyke, Chris, Yang, Samuel, Lloyd, Thomas, Thompson, Rik, & Momot, Konstantin (2018) T1-based sensing of mammographic density using single-sided portable NMR. Magnetic Resonance in Medicine, 80(3), pp. 1243-1251.
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Description
Purpose A single-sided NMR instrument was used to investigate the ability of the T1 relaxation constant to distinguish between regions of low and high mammographic density in human breast tissue. Methods Measurements were performed on 5 breast slices obtained from 3 women undergoing breast reduction surgery or prophylactic mastectomy. Results T1 values measured in regions of high mammographic density in both the full breast slices (T1 = 170 ± 30 ms) and excised regions (T1 = 160 ± 30 ms) were found to be significantly different (P < .001) from those measured in regions of low mammographic density, in which T1 = 120 ± 10 ms was observed both in full slices and excised regions. There was no statistically significant difference between the T1 values measured in the full breast slices and those measured in the excised regions. Conclusion The findings suggest that portable NMR may provide a low-cost means of assessing mammographic density in vivo.
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| ID Code: | 223505 | ||||
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| Item Type: | Contribution to Journal (Journal Article) | ||||
| Refereed: | Yes | ||||
| ORCID iD: |
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| Measurements or Duration: | 9 pages | ||||
| Keywords: | Breast tissue, In vivo, Mammographic density, Portable NMR | ||||
| DOI: | 10.1002/mrm.27098 | ||||
| ISSN: | 1522-2594 | ||||
| Pure ID: | 33338151 | ||||
| Divisions: | Past > QUT Faculties & Divisions > Faculty of Health Past > Institutes > Institute of Health and Biomedical Innovation Past > QUT Faculties & Divisions > Science & Engineering Faculty |
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| Copyright Owner: | Consult author(s) regarding copyright matters | ||||
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| Deposited On: | 06 Nov 2021 17:54 | ||||
| Last Modified: | 08 Feb 2025 17:27 |
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