Freestanding, Multilayered and Biomimetic Vasculature-on-a-Chip Model by 3D-Printed Porous Mold
Ching, Terry, Vasudevan, Jyothsna, Chang, Shu Yung, Tan, Hsih Yin, Lim, Chwee Teck, Fernandez, Javier G., Ng, Jun Jie, Toh, Yi Chin, & Hashimoto, Michinao (2021) Freestanding, Multilayered and Biomimetic Vasculature-on-a-Chip Model by 3D-Printed Porous Mold. In MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, San Diego, CA, pp. 97-98.
Description
Anatomically and biologically relevant vascular models are critical to progress our understanding of cardiovascular diseases (CVDs) that can lead to effective therapeutics. Current vascular models either lack biomimetic vascular tissue structures or anatomically accurate architectures. In this work, we developed a technique to fabricate anatomical accurate vascular models (i.e., freestanding, branching, multilayered, perfusable, mechanically stretchable) with the option of customizing the bioink blend to improve compatibility with relevant cells and the mechanical properties.
Impact and interest:
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| ID Code: | 235280 | ||
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| Item Type: | Chapter in Book, Report or Conference volume (Conference contribution) | ||
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| Additional Information: | Funding Information: T.C. thanks the Ministry of Education (MOE), Singapore, for awarding the President's Graduate Fellowship. M.H. acknowledges MOE, Singapore, for the project funding (MOE2019-T2-2-192). Y.C.T. acknowledges Australian Research Council (ARC) Future Fellowship (FT180100157) and Discovery Project (DP200101658). | ||
| Measurements or Duration: | 2 pages | ||
| Event Title: | International Conference on Miniaturized Systems for Chemistry and Life Sciences | ||
| Event Dates: | 2021-10-10 - 2021-10-14 | ||
| Event Location: | Palm Springs, United States | ||
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| Keywords: | 3D-printing, Microfluidics, Vasculature-on-a-chip | ||
| ISBN: | 9781733419031 | ||
| Pure ID: | 115470713 | ||
| Divisions: | Current > Research Centres > Centre for Biomedical Technologies Current > QUT Faculties and Divisions > Faculty of Engineering Current > Schools > School of Mechanical, Medical & Process Engineering |
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| Funding Information: | T.C. thanks the Ministry of Education (MOE), Singapore, for awarding the President's Graduate Fellowship. M.H. acknowledges MOE, Singapore, for the project funding (MOE2019-T2-2-192). Y.C.T. acknowledges Australian Research Council (ARC) Future Fellowship (FT180100157) and Discovery Project (DP200101658). | ||
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| Copyright Owner: | 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences | ||
| Copyright Statement: | This work is covered by copyright. Unless the document is being made available under a Creative Commons Licence, you must assume that re-use is limited to personal use and that permission from the copyright owner must be obtained for all other uses. If the document is available under a Creative Commons License (or other specified license) then refer to the Licence for details of permitted re-use. It is a condition of access that users recognise and abide by the legal requirements associated with these rights. If you believe that this work infringes copyright please provide details by email to qut.copyright@qut.edu.au | ||
| Deposited On: | 20 Sep 2022 11:30 | ||
| Last Modified: | 23 Apr 2026 05:46 |
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