Synthetic 3D brain MRI generation for evaluation and improvement of cortical thickness estimation methods

(2023) Synthetic 3D brain MRI generation for evaluation and improvement of cortical thickness estimation methods. PhD thesis, Queensland University of Technology.

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Description

This thesis was a step forward in developing tools and methods for very accurate measurements of brain atrophy which is essential for studying neurodegenerative diseases. The proposed methods are based on generative artificial intelligence (AI) that utilises cortex meshes to introduce controlled and quantified changes in different brain regions. This thesis provided the world-first benchmark for methods measuring cortical thinning and enabled the research community to evaluate their cortical thickness estimation methods against it.

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53 since deposited on 03 Mar 2023
28 in the past twelve months

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ID Code: 238363
Item Type: QUT Thesis (PhD)
Supervisor: Bradley, Andrew P. & Fookes, Clinton
ORCID iD:
Rusak, Filiporcid.org/0000-0001-5615-5245
Keywords: 3D Synthetic Brain MRI, Generative adversarial networks, Synthetic atrophy, Data augmentation, Partial volume maps, Cortical thickness estimation
DOI: 10.5204/thesis.eprints.238363
Pure ID: 126525560
Divisions: Current > QUT Faculties and Divisions > Faculty of Engineering
Current > Schools > School of Electrical Engineering & Robotics
Institution: Queensland University of Technology
Deposited On: 03 Mar 2023 05:24
Last Modified: 03 Mar 2023 05:24