Cost-effectiveness of a policy-based intervention to reduce melanoma and other skin cancers associated with indoor tanning

Eden, Martin, Hainsworth, Rob, , Epton, Tracy, Lorigan, Paul, Rhodes, Lesley E., Marais, Richard, Green, Adele C., & Payne, Katherine (2022) Cost-effectiveness of a policy-based intervention to reduce melanoma and other skin cancers associated with indoor tanning. British Journal of Dermatology, 187(1), pp. 105-114.

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Description

Background: The use of indoor tanning devices causes melanoma and other skin cancers with resulting morbidity, mortality and increased healthcare costs. Policymakers require robust economic evidence to inform decisions about a possible ban of such devices to mitigate these burdens. Objectives: To assess the health costs and consequences of introducing a policy-based intervention across England to ban commercial indoor tanning with an accompanying public information campaign. Methods: A cost-effectiveness analysis, adopting a healthcare system perspective, was conducted using a decision model to track a national cohort of 18-year-olds over a lifetime time horizon. A nationwide ban on commercial indoor tanning combined with a public information campaign (the policy-based intervention) was compared with the status quo of availability of commercial indoor tanning. The expected costs (currency, GBP; price year, 2019) and quality-adjusted life-years (QALYs) were calculated. Net monetary benefit (NMB) (net benefit measured in cost compared with an accepted threshold) and net health benefit (NHB) (net gain in QALYs compared with an accepted threshold) of implementation were calculated. A probabilistic sensitivity analysis was used to calculate the probability that the intervention was cost-effective. Results: Compared with the current situation, a ban on commercial indoor tanning combined with a public information campaign would result in 1206 avoided cases of melanoma, 207 fewer melanoma deaths and 3987 averted cases of keratinocyte cancers over the lifetime of all 18-year-olds (n = 618 873) living in England in 2019. An additional 497 QALYs would be realized along with healthcare cost-savings of £697 858. This intervention would result in an NMB of £10.6m and an NHB of 530 QALYS. Multiple sensitivity analyses confirmed the robustness of the findings. At a cost-effectiveness threshold of £20 000, there is a 99% likelihood of this policy-based intervention being cost-effective. Conclusions: The implementation of a ban on commercial indoor tanning across England with an accompanying public information campaign would be an effective use of healthcare resources.

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ID Code: 241329
Item Type: Contribution to Journal (Journal Article)
Refereed: Yes
ORCID iD:
Gordon, Louisa G.orcid.org/0000-0002-3159-4249
Additional Information: Funding Information: sources This work was supported by a Research Town Hall seed grant from the Manchester Cancer Research Centre and its partners, Faculty of Biology, Medicine and Health, University of Manchester and the Christie NHS Trust Charity. This work was supported by Cancer Research UK (A27412 and A22902), the Wellcome Trust (100282/Z/12/Z) and the European Research Council (ERC Advanced Grant No. 671262).Thanks to Megan Grant for coordination and assistance with the project. Neyha Javed, an intern at the Manchester Centre for Health Economics during 2020, assisted with the literature reviews. L.E.R. acknowledges the support of the National Institute for Health Research Manchester Biomedical Research Centre.
Measurements or Duration: 10 pages
DOI: 10.1111/bjd.21046
ISSN: 0007-0963
Pure ID: 139265446
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Schools > School of Nursing
Funding Information: Thanks to Megan Grant for coordination and assistance with the project. Neyha Javed, an intern at the Manchester Centre for Health Economics during 2020, assisted with the literature reviews. L.E.R. acknowledges the support of the National Institute for Health Research Manchester Biomedical Research Centre. sources This work was supported by a Research Town Hall seed grant from the Manchester Cancer Research Centre and its partners, Faculty of Biology, Medicine and Health, University of Manchester and the Christie NHS Trust Charity. This work was supported by Cancer Research UK (A27412 and A22902), the Wellcome Trust (100282/Z/12/Z) and the European Research Council (ERC Advanced Grant No. 671262).Thanks to Megan Grant for coordination and assistance with the project. Neyha Javed, an intern at the Manchester Centre for Health Economics during 2020, assisted with the literature reviews. L.E.R. acknowledges the support of the National Institute for Health Research Manchester Biomedical Research Centre.
Copyright Owner: 2022 The Authors.
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Deposited On: 11 Jul 2023 06:26
Last Modified: 20 Jun 2024 16:58