Development of a translational bioengineered microenvironment model to advance pre-clinical acute myeloid leukaemia research
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Description
Acute myeloid leukaemia is a highly diverse blood cancer associated with a poor 5-year survival rate of less than 30 per cent, necessitating the development of new treatments for this disease. Modelling leukaemia in three-dimensions may allow for drug testing that is more representative of the human tumour microenvironment than traditional cell culture. In this project, a three-dimensional hydrogel model was developed that can be used for cell expansion and for drug testing.
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| ID Code: | 241518 |
|---|---|
| Item Type: | QUT Thesis (Master of Philosophy) |
| Supervisor: | Bray, Laura & Ravichandran, Akhilandeshwari |
| Keywords: | Leukaemia, Hydrogels, Tissue engineering, Tumour microenvironment, Cell culture |
| DOI: | 10.5204/thesis.eprints.241518 |
| Pure ID: | 139849471 |
| Divisions: | Current > QUT Faculties and Divisions > Faculty of Engineering Current > Schools > School of Mechanical, Medical & Process Engineering |
| Institution: | Queensland University of Technology |
| Deposited On: | 14 Jul 2023 03:08 |
| Last Modified: | 07 Jul 2024 14:00 |
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