Vertebral body tethering for idiopathic scoliosis: a systematic review and meta-analysis
Roser, Megan J, Askin, Geoffrey N, Labrom, Robert D, Zahir, Syeda Farah, Izatt, Maree, & Little, J Paige (2023) Vertebral body tethering for idiopathic scoliosis: a systematic review and meta-analysis. Spine Deformity, 11(6), pp. 1297-1307.
Open access copy at publisher website
Description
<p>Purpose: Vertebral body tethering (VBT) is a recent procedure to correct and reduce spinal curves in skeletally immature patients with adolescent idiopathic scoliosis (AIS). The purpose of this systematic review and meta-analysis is to determine the expected curve reduction and potential complications for adolescent patients after VBT. Methods: PubMed, Embase, Google Scholar and Cochrane databases were searched until February 2022. Records were screened against pre-defined inclusion and exclusion criteria. Data sources were prospective and retrospective studies. Demographics, mean differences in Cobb angle, surgical details and complication rates were recorded. Meta-analysis was conducted using a random-effects model. Results: This systematic review includes 19 studies, and the meta-analysis includes 16 of these. VBT displayed a statistically significant reduction in Cobb angle from pre-operative to final (minimum 2 years) measurements. The initial mean Cobb angle was 47.8° (CI 95% 42.9–52.7°) and decreased to 22.2° (CI 95% 19.9–24.5°). The mean difference is − 25.8° (CI 95% − 28.9–22.7) (p < 0.01). The overall complication rate was 23% (CI 95% 14.4–31.6%), the most common complication was tether breakage 21.9% (CI 95% 10.6–33.1%). The spinal fusion rate was 7.2% (CI 95% 2.3–12.1%). Conclusion: VBT results in a significant reduction of AIS at 2 years of follow-up. Overall complication rate was relatively high although the consequences of the complications are unknown. Further research is required to explore the reasons behind the complication rate and determine the optimal timing for the procedure. VBT remains a promising new procedure that is effective at reducing scoliotic curves and preventing spinal fusion in the majority of patients. Level of evidence: Systematic review of Therapeutic Studies with evidence level II–IV.</p>
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ID Code: | 241646 | ||||||
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Item Type: | Contribution to Journal (Review article) | ||||||
Refereed: | Yes | ||||||
ORCID iD: |
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Measurements or Duration: | 11 pages | ||||||
Keywords: | vertebral body tethering, adolescent idiopathic scoliosis, systematic review, orthopaedics, surgery, fusionless surgery, growth friendly surgery | ||||||
DOI: | 10.1007/s43390-023-00723-9 | ||||||
ISSN: | 2212-134X | ||||||
Pure ID: | 140095427 | ||||||
Divisions: | Current > Research Centres > Centre for Biomedical Technologies Current > QUT Faculties and Divisions > Faculty of Engineering Current > Schools > School of Mechanical, Medical & Process Engineering |
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Copyright Owner: | 2023 The Authors | ||||||
Copyright Statement: | This work is covered by copyright. Unless the document is being made available under a Creative Commons Licence, you must assume that re-use is limited to personal use and that permission from the copyright owner must be obtained for all other uses. If the document is available under a Creative Commons License (or other specified license) then refer to the Licence for details of permitted re-use. It is a condition of access that users recognise and abide by the legal requirements associated with these rights. If you believe that this work infringes copyright please provide details by email to qut.copyright@qut.edu.au | ||||||
Deposited On: | 18 Jul 2023 05:46 | ||||||
Last Modified: | 09 Feb 2025 11:01 |
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