Therapeutic potential of boosting NAD+ levels in aging and age-related bone loss
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Yogita Prashant Sonar Thesis. Available under License Creative Commons Attribution Non-commercial No Derivatives 4.0. |
Description
This thesis presents a study exploring the use of Nicotinamide Mononucleotide (NMN) to boost Nicotinamide Adenine Dinucleotide (NAD) levels and its potential in combating aging and age-related bone loss. NAD, a vital cellular coenzyme, regulates DNA repair and energy production. As NAD declines with age, it contributes to various age-related health problems. In a four-week animal model study, we investigated NMN supplementation's ability to raise NAD levels and its implications for countering age-related bone loss. Our results offer promising insights into the therapeutic potential of NMN for addressing NAD-related aging issues.
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| ID Code: | 243826 |
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| Item Type: | QUT Thesis (Master of Philosophy) |
| Supervisor: | Prasadam, Indira & Crawford, Ross |
| Keywords: | NAD, NMN, Aging, NMNAT 1, Bone |
| DOI: | 10.5204/thesis.eprints.243826 |
| Pure ID: | 147121215 |
| Divisions: | Current > QUT Faculties and Divisions > Faculty of Engineering Current > Schools > School of Mechanical, Medical & Process Engineering |
| Institution: | Queensland University of Technology |
| Deposited On: | 12 Oct 2023 04:46 |
| Last Modified: | 12 Oct 2023 04:47 |
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