The effects of long-term sucrose consumption on olfactory neurogenesis and neuroinflammation
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Description
The involvement of sugar consumption in obesity has been well established, however the effect of long-term sucrose consumption on the brain structures associated with appetite remains unclear. Here we used the olfactory system and brain neurogenic areas to investigate the effect of long-term sucrose consumption on forebrain neurogenesis and glial cells. We found that sucrose consumption had no overall effect on olfactory neurogenesis, however there was an increase in a subpopulation of interneurons in the olfactory bulb. Of the glial cells, sucrose consumption did not affect the microglia, however it changed the behaviour of astrocytes in some brain structures.
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| ID Code: | 244721 |
|---|---|
| Item Type: | QUT Thesis (Master of Philosophy) |
| Supervisor: | Chehrehasa, Fatemeh, Bartlett, Selena, Belmer, Arnauld, & |
| Keywords: | Adolescent, Granule Cell, Juxtaglomerular Cell, Neural Stem Cell, Neuroinflammation, Neurogenesis, Olfactory Bulb, Rostral Migratory Stream, Subventricular Zone, Sucrose |
| DOI: | 10.5204/thesis.eprints.244721 |
| Pure ID: | 149892441 |
| Divisions: | Current > QUT Faculties and Divisions > Faculty of Health Current > Schools > School of Biomedical Sciences |
| Institution: | Queensland University of Technology |
| Deposited On: | 27 Nov 2023 13:50 |
| Last Modified: | 27 Nov 2023 13:50 |
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