Uncovering the genetic drivers of cutaneous melanoma and its risk factors
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Description
My thesis leverages statistical methods within large genotyped populations to identify genes associated with an increased risk of melanoma. Additionally, I incorporate the genes I identify with previously reported findings to generate polygenic risk scores, which can help stratify a population based on peoples genetic susceptibility to melanoma.
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| ID Code: | 247498 |
|---|---|
| Item Type: | QUT Thesis (PhD by Publication) |
| Supervisor: | Law, Matthew, MacGregor, Stuart, & Nyholt, Dale |
| Keywords: | Genetics, Melanoma, Polygenic Risk Score, Genome-wide association study, Skin cancer, Melanoma risk factors, Nevus count, Photoaging |
| DOI: | 10.5204/thesis.eprints.247498 |
| Pure ID: | 165388737 |
| Divisions: | Current > QUT Faculties and Divisions > Faculty of Health Current > Schools > School of Biomedical Sciences |
| Institution: | Queensland University of Technology |
| Deposited On: | 25 Mar 2024 05:24 |
| Last Modified: | 25 Mar 2024 05:25 |
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