Hydrogen ion concentration of human tears: Effects of prolonged eye closure

Carney, Leo G. & Hill, Richard M. (1976) Hydrogen ion concentration of human tears: Effects of prolonged eye closure. Archives of Ophthalmology, 36(12), pp. 835-838.


Using a closed chamber microelectrode technique, human tear hydrogen ion concentration was measured following periods of eye closure of 6 to 8 hours and then compared with normal open eye findings from the same patients. Closed eye tears were found to be significantly more acid (average age difference = 26 nM/1) and required some 3 to 4 hours to return to average open eye levels. The population rate for this return averaged 6.9 nM/1/hr. This degree of acid shift measured for prolonged eye closure, however, remained, for the average patient, well within comfort limits commonly cited, and appeared insufficient to distrub the water content or optical parameters of hydrophilic polymers in common use today for therapeutic or cosmetic purposes.

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4 citations in Web of Science®
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ID Code: 3098
Item Type: Journal Article
Refereed: Yes
Additional Information: Self-archiving is not yet supported by this publisher.
For more information, please refer to the journal’s website (see link) or contact the author. Author contact details: l.carney@qut.edu.au
Additional URLs:
Keywords: Tears, physiology, Adult, Eyelids, physiology, Female, Humans, Hydrogen, Ion Concentration, Male, Ocular Physiology, Optometry, Tears/metabolism
ISSN: 0003-9950
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 1976 American Medical Association
Deposited On: 19 Jan 2006 00:00
Last Modified: 15 Jan 2009 06:54

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