Corneal topography and myopia: A cross-sectional study

Carney, Leo G., Mainstone, Julia C., & Henderson, Beth A. (1997) Corneal topography and myopia: A cross-sectional study. Investigative Ophthalmology and Visual Science, 38(2), pp. 311-320.


PURPOSE: Central corneal curvature is known to vary with refractive error, but the relation between corneal topography and ametropia is less clear. The current study was conducted to determine whether a relation exists between corneal asphericity and myopia. Associations between corneal asphericity and each of the components of refraction also were examined. METHODS: Corneal asphericity and apical radius of curvature were determined for 113 eyes (spherical equivalent refractive error +0.25 diopter [D] to -9.88 D) by fitting a conicoid equation to videokeratoscopic data. Computerized videokeratoscopic images were recorded using a Topographic Modeling System. Keratometry also was performed on each eye. Anterior chamber depth, lens thickness, vitreous chamber depth, and axial length were measured with a hand-held biometric ruler. RESULTS: A low but statistically significant positive correlation was found between corneal asphericity (Q) and spherical equivalent refractive error (r = 0.275, P < 0.01). Significant relations also were observed between Q and vitreous chamber depth (r = 0.17, P < 0.1) and between Q and axial length (r = 0.24, P < 0.05). The association between Q and corneal radius of curvature was found not to be significant. Eyes with higher levels of myopia had steeper central corneal curvatures, deeper anterior and vitreous chambers, and greater axial lengths. CONCLUSIONS: A tendency for the cornea to flatten less rapidly in the periphery with increasing myopia was shown. Decreased peripheral corneal flattening also was observed in association with increasing vitreous chamber depth and increasing axial length. These findings have implications for refractive surgery outcomes, schematic eye modeling, contact lens design, and ocular aberration analysis.

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ID Code: 3163
Item Type: Journal Article
Refereed: Yes
Additional Information: For more information, please refer to the journal's website (see link) or contact the author. Author contact details:
Additional URLs:
Keywords: Cornea/, pathology, Myopia/, pathology, Adolescent, Adult, Anterior Chamber/pathology, Comparative Study, Cross, Sectional Studies, Eye/pathology, Female, Humans, Image Processing, Computer, Assisted, Male, Middle Aged, Refractive Errors/pathology, Research Support, Non, U, S, Gov't
ISSN: 0146-0404
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 1997 Association for Research in Vision and Ophthalmology
Deposited On: 30 Jan 2006 00:00
Last Modified: 15 Jan 2009 06:54

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