Menstrual cycle variations of corneal topography and thickness

Kiely, Patricia M., Carney, Leo G., & Smith, George (1983) Menstrual cycle variations of corneal topography and thickness. American Journal of Optometry and Physiological Optics, 60(10), pp. 822-829.



Two studies were performed to investigate dimensional stability of the cornea throughout the female menstrual cycle. In the first study, changes of corneal curvature, topography, and thickness were measured for six women for one complete menstrual cycle. Steepening of horizontal and vertical curvatures occurred at the beginning of the cycle, and flattening occurred after ovulation. Corneal thickening occurred on the second day of the cycle and around the time of ovulation, then thinning and another slight thickening on day 21. In the second study, more detailed information was sought on the timing of corneal thickness changes throughout any cycle. Corneal thickness was studied for two subjects throughout three consecutive cycles. Both subjects showed a slight decrease in thickness toward the end of the menses; thickening occurred at ovulation followed by thinning. Thickening also occurred 4 days after ovulation. Consideration of changes in urine levels of estrogen and pregnanediol suggests that rises in estrogen are accompanied by increases in corneal thickness.

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ID Code: 3190
Item Type: Journal Article
Refereed: Yes
Additional Information:
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Keywords: Menstruation, Cornea/, physiology, Adult, Cornea/anatomy & histology, Cornea/drug effects, Estrogens/pharmacology, Estrogens/urine, Female, Humans, Ovulation, Pregnanediol/urine
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 1983 American Academy of Optometry
Copyright Statement: Reproduced in accordance with the copyright policy of the publisher.
Deposited On: 02 Jan 2007 00:00
Last Modified: 09 Jun 2010 12:29

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