Dehydration of hydrogel lenses during overnight wear

Brennan, Noel A., Lowe, Russell, Efron, Nathan, Ungerer, Jan L., & Carney, Leo G. (1987) Dehydration of hydrogel lenses during overnight wear. American Journal of Optometry and Physiological Optics, 64(7), pp. 534-539.



We studied the extent of dehydration of hydrogel lenses during overnight wear. Seven subjects used a hand refractometer to measure the water content of five different lenses (Hydron zero-6 (nominal water content 38.6%), -0.50 D; Snoflex 50 (52.5%), -0.50 and + 15.00 D, and Hydron Z-67 (67.5%), -0.50 and + 15.00 D) before and after 7 h of both open- and closed-eye wear. No statistically significant difference was observed in dehydration between open and closed eye lens wear. Thick and thin lenses made of the same material were found to dehydrate to an equal extent. Contrary to expectations, the medium water content Snoflex 50 lenses displayed a greater absolute decrease in water content than the higher water content Hydron Z-67 lenses (p less than 0.01). Factors that may influence the extent of dehydration under open- and closed-eye wearing conditions, and the clinical implications of these results, are discussed.

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18 citations in Scopus
9 citations in Web of Science®
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ID Code: 3193
Item Type: Journal Article
Refereed: Yes
Additional Information:
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Keywords: Contact Lenses, Polyethylene Glycols, Sleep, Water, Adult, Analysis of Variance, Female, Humans, Hydrogel, Male, Refractometry, Research Support, Non, U, S, Gov't
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 1987 The American Academy of Optometry
Copyright Statement: Reproduced in accordance with the copyright policy of the publisher.
Deposited On: 20 Mar 2006 00:00
Last Modified: 10 Aug 2011 13:21

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