Prostaglandin-inhibitor naproxen does not affect contact lens-induced changes in the human corneal endothelium

Efron, Nathan, Holden, Brien A., & Vannas, Antti (1984) Prostaglandin-inhibitor naproxen does not affect contact lens-induced changes in the human corneal endothelium. American Journal of Optometry and Physiological Optics, 61(12), pp. 741-744.


A randomized, double-masked, placebo-controlled study was conducted to determine the effect of the prostaglandin-inhibitor naproxen on the bleb response of the corneal endothelium during hydrogel contact lens wear. Naproxen did not significantly alter the bleb response. This finding suggests that the endothelial bleb response is not prostaglandin-mediated.

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2 citations in Scopus
3 citations in Web of Science®
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ID Code: 3337
Item Type: Journal Article
Refereed: Yes
Additional Information: This journal is now called Optometry and Vision Science and is published by Lippincott Williams & Wilkins.
Self-archiving of the author-version is not yet supported by this publisher.
For more information, please refer to the journal’s website (see hypertext link) or contact the author.
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Keywords: Prostaglandin Antagonists, Contact Lenses/, adverse effects, Cornea/, pathology, Naproxen/, therapeutic use, Adolescent, Adult, Endothelium/pathology, Evaluation Studies, Female, Humans, Male
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 1984 Lippincott Williams & Wilkins
Deposited On: 19 Jul 2006 00:00
Last Modified: 10 Aug 2011 14:42

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