Microbial flora in eyes of current and former contact lens wearers

Fleiszig, Suzanne M. & Efron, Nathan (1992) Microbial flora in eyes of current and former contact lens wearers. Journal of clinical microbiology, 30(5), pp. 1156-1161.

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Microbial flora from the right eye conjunctival sac of 84 consecutively presenting contact lens patients were compared with cultures from both surfaces of their lens after aseptic removal and with the flora of their storage cases. Similar results were obtained from contact lens and conjunctival cultures of each individual; however, there was no correlation between storage case isolates and lens or conjunctival flora, suggesting that in uncomplicated lens wear, the eye is highly efficient in eradicating microorganisms introduced via handling. Conjunctival flora during daily contact lens wear was similar to the conjunctival flora of a matched control group of non-lens wearers. However, bacteria that are considered to be part of the normal ocular flora were isolated significantly more often from former contact lens wearers. The data also indicated that the use of nonperoxide chemical lens disinfection was associated with a higher proportion of positive cultures for pathogenic microorganisms than the use of other forms of disinfection, for both current and former contact lens wearers. The isolation of potential pathogens was particularly common among elderly subjects using thick contact lenses for extended wear. These changes to conjunctival flora may contribute to the increased risk of ocular infection associated with contact lens wear.

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54 citations in Web of Science®
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ID Code: 3376
Item Type: Journal Article
Refereed: Yes
Additional Information: Articles free to read on journal website after 6 months
Additional URLs:
Keywords: Contact Lenses, /adverse effects, Bacteria/, isolation & purification, Conjunctiva/, microbiology, Adult, Aged, Bacterial Infections/etiology, Eye Diseases/etiology, Female, Humans, Male, Middle Aged, Research Support, Non, U, S, Gov't
ISSN: 0095-1137
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 1992 American Society for Microbiology
Copyright Statement: The contents of this journal can be freely accessed online via the journal’s web page (see link) four months after publication.
Deposited On: 15 Feb 2006 00:00
Last Modified: 05 Feb 2015 00:38

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