Conjunctival flora in extended wear of rigid gas permeable contact lenses

Fleiszig, Suzanne M.J. & Efron, Nathan (1992) Conjunctival flora in extended wear of rigid gas permeable contact lenses. Optometry and Vision Science, 69(5), pp. 354-357.


A longitudinal study was performed to examine the effect of rigid gas permeable (RGP) contact lenses (Boston Equalens II and Quantum II) on the conjunctival flora of 45 young healthy subjects. Microbial flora were determined before delivery of lenses. Subjects wore lenses on an extended wear basis, removing them every 7 days for cleaning and disinfection. Cultures were repeated after 2 months of lens wear and the microbial flora were found to be significantly altered compared to the prelens wear results (0.05 greater than p greater than 0.02). Changes to conjunctival flora included an increase in the number of eyes from which potentially pathogenic microorganisms were isolated, an increase in the number of eyes that were culture-negative, and a decrease in the number of eyes harboring only normal conjunctival flora. The increase in potentially pathogenic flora was not specific for Gram-negative bacteria, which are most often associated with infectious keratitis during contact lens wear.

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17 citations in Scopus
15 citations in Web of Science®
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ID Code: 3377
Item Type: Journal Article
Refereed: Yes
Additional Information: For more information, please refer to the journal’s website (see link) or contact the author. Author contact details:
Additional URLs:
Keywords: Contact Lenses, Extended, Wear, Bacteria/, isolation & purification, Conjunctiva/, microbiology, Adolescent, Adult, Female, Humans, Longitudinal Studies, Male, Microbiological Techniques, Research Support, Non, U, S, Gov't
ISSN: 1040-5488
Subjects: Australian and New Zealand Standard Research Classification > MEDICAL AND HEALTH SCIENCES (110000) > OPTOMETRY AND OPHTHALMOLOGY (111300)
Divisions: Current > QUT Faculties and Divisions > Faculty of Health
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 1992 Lippincott Williams & Wilkins
Deposited On: 10 Feb 2006 00:00
Last Modified: 10 Aug 2011 14:07

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