Travelling Waves in a Wound Healing Assay

, , & (2004) Travelling Waves in a Wound Healing Assay. Applied Mathematics Letters, 17(5), pp. 575-580.

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Description

Several authors have predicted that cell propagation in a number of biological contexts, for example, wound healing, tumour cell invasion, angiogenesis etc., occurs due to a constant speed travelling wave of invasion. The analyses of these models to arrive at this prediction is, in many cases, essentially an extension of the classical analysis of Fisher's equation. Here, we show that a very simple wound healing assay does indeed give rise to constant speed travelling waves. To our knowledge, this is the first verification of Fisher's equation in a medical context.

Impact and interest:

138 citations in Scopus
141 citations in Web of Science®
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ID Code: 3452
Item Type: Contribution to Journal (Journal Article)
Refereed: Yes
ORCID iD:
McElwain, Donaldorcid.org/0000-0002-7046-0251
Measurements or Duration: 6 pages
DOI: 10.1016/S0893-9659(04)90128-0
ISSN: 0893-9659
Pure ID: 34190001
Divisions: Past > QUT Faculties & Divisions > Faculty of Health
Past > QUT Faculties & Divisions > Faculty of Science and Technology
Copyright Owner: Consult author(s) regarding copyright matters
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Deposited On: 28 Apr 2008 00:00
Last Modified: 03 Jun 2024 19:57