Bayesian survival analysis using gene expression
Description
This thesis developed and applied Bayesian models for the analysis of survival data. The gene expression was considered as explanatory variables within the Bayesian survival model which can be considered the new contribution in the analysis of such data. The censoring factor that is inherent of survival data has also been addressed in terms of its impact on the fitting of a finite mixture of Weibull distribution with and without covariates. To investigate this, simulation study were carried out under several censoring percentages. Censoring percentage as high as 80% is acceptable here as the work involved high dimensional data. Lastly the Bayesian model averaging approach was developed to incorporate model uncertainty in the prediction of survival.
Impact and interest:
Citation counts are sourced monthly from Scopus and Web of Science® citation databases.
These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.
Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.
Full-text downloads:
Full-text downloads displays the total number of times this work’s files (e.g., a PDF) have been downloaded from QUT ePrints as well as the number of downloads in the previous 365 days. The count includes downloads for all files if a work has more than one.
| ID Code: | 62666 |
|---|---|
| Item Type: | QUT Thesis (PhD by Publication) |
| Supervisor: | Mengersen, Kerrie & McGree, James |
| Keywords: | Bayesian Modelling, Survival Analysis, Weibull Distribution, Bayesian Model Averaging, Gene Expression |
| Divisions: | Past > QUT Faculties & Divisions > Science & Engineering Faculty Current > Schools > School of Mathematical Sciences |
| Institution: | Queensland University of Technology |
| Deposited On: | 23 Sep 2013 03:22 |
| Last Modified: | 05 Sep 2017 14:41 |
Export: EndNote | Dublin Core | BibTeX
Repository Staff Only: item control page
CORE (COnnecting REpositories)
CORE (COnnecting REpositories)