Feasibility of ranking articular cartilage conditions with non-destructive near-infrared spectroscopy with extension to the Mankin grading system
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Hayley Moody Thesis
(PDF 26MB)
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Description
Grading osteoarthritic tissue has, until now, been a laboratory process confined to research activities. This thesis establishes a scientific protocol that extends osteoarthritic tissue ranking to surgical practice. The innovative protocol, which now incorporates the structural degeneration of collagen, enhances the traditional Modified Mankin ranking system, enabling its application to real time decision during surgery. Because it is fast and without time consuming laboratory process, it would potentially enable the cataloguing of tissues in osteoarthritic joints in all compartments of diseased joints during surgery for epistemological study and insight into the manifestation of osteoarthritis across age, gender, occupation, physical activities and race.
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| ID Code: | 62760 |
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| Item Type: | QUT Thesis (PhD) |
| Supervisor: | Oloyede, Kunle & Crawford, Ross |
| Keywords: | articular cartilage, histology, Mankin, near infrared spectroscopy, osteoarthritis, grading, second harmonic generation, pannus, collagen aggregation, degeneration |
| Divisions: | Past > Institutes > Institute of Health and Biomedical Innovation Past > QUT Faculties & Divisions > Science & Engineering Faculty Past > Schools > School of Chemistry, Physics & Mechanical Engineering |
| Institution: | Queensland University of Technology |
| Deposited On: | 23 Sep 2013 03:34 |
| Last Modified: | 10 Dec 2021 02:44 |
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