Preparation and characterization of interpenetrating phased TCP/HA/PLGA composites
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Description
The purpose of this study was to fabricate composites consisting of three interpenetrating networks: tricalcium phosphate (TCP), hydroxyapatite (HA), and poly(DL-lactide-co-glycolide) (PLGA). The porous TCP network was first produced by coating a polyurethane (PU) foam with hydrolysable alpha-TCP slurry. The HA network was derived from a calcium phosphate cement (CPC) filled in the porous TCP network. The remaining open pore network in the HA/TCP composite was further infiltrated with a PLGA network. The three sets of spatially continuous networks would have different biodegradation rates and thus bone tissue would grow towards the fastest biodegrading network while the remaining networks still maintaining their geometrical shape and carrying the physiological load for the tissue ingrowth.
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| ID Code: | 6758 |
|---|---|
| Item Type: | Contribution to Journal (Journal Article) |
| Refereed: | Yes |
| Measurements or Duration: | 6 pages |
| Keywords: | Calcium Phosphate Cement, Interpenetrating Composite, Poly(dl-lactide-co-glycolide), Tricalcium Phosphate |
| DOI: | 10.1016/j.matlet.2005.07.062 |
| ISSN: | 0167-577X |
| Pure ID: | 34309629 |
| Divisions: | Past > QUT Faculties & Divisions > Faculty of Built Environment and Engineering Past > Schools > School of Engineering Systems |
| Copyright Owner: | Consult author(s) regarding copyright matters |
| Copyright Statement: | This work is covered by copyright. Unless the document is being made available under a Creative Commons Licence, you must assume that re-use is limited to personal use and that permission from the copyright owner must be obtained for all other uses. If the document is available under a Creative Commons License (or other specified license) then refer to the Licence for details of permitted re-use. It is a condition of access that users recognise and abide by the legal requirements associated with these rights. If you believe that this work infringes copyright please provide details by email to qut.copyright@qut.edu.au |
| Deposited On: | 30 Mar 2007 00:00 |
| Last Modified: | 01 Jul 2024 21:50 |
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