Use of a matrix scaffold for tissue engineering and bone regeneration

Bartold, P. Mark & Xiao, Yin (2003) Use of a matrix scaffold for tissue engineering and bone regeneration. In Ellingsen, Jan Eirik & Lyngstaadas, S. Petter (Eds.) Bio-implant interface : improving biomaterials and tissue reactions. CRC Press, Boca Raton, Fla., pp. 243-254.


The regeneration of bone defects resulting from tumors, diseases, infections, trauma, biochemical disorders, and abnormal skeletal development posese a significant clinical challenge. Over the years, many bone graft substitites including autografts, allograft, and synthetic materials have been developed. In this chapter, we demonstrated how cells from avelolar bone retain their osteogenic properties in a three-dimensional collagen scvaffold and subsequently synthesize a bone matrix which, after implantation, can induce new bone formation in critical size calvarial defects.

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ID Code: 9181
Item Type: Book Chapter
Additional Information: For more information about this book please refer to the publisher's website (see link) or contact the author. Author contact details :
Additional URLs:
ISBN: 0849314747
Subjects: Australian and New Zealand Standard Research Classification > BIOLOGICAL SCIENCES (060000) > BIOCHEMISTRY AND CELL BIOLOGY (060100) > Cellular Interactions (incl. Adhesion Matrix Cell Wall) (060106)
Divisions: Past > QUT Faculties & Divisions > Faculty of Built Environment and Engineering
Current > Institutes > Institute of Health and Biomedical Innovation
Copyright Owner: Copyright 2003 CRC Press
Deposited On: 27 Aug 2007 00:00
Last Modified: 21 Apr 2010 17:03

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