Chlamydial infertility in women: Diagnosis, epidemiology and immune response
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Shruti Menon Thesis (PDF 2MB) |
Description
This project primarily focused on the development of a novel, non-invasive peptide-based ELISA to diagnose C. trachomatis-related infertility in women. In this study, an in silico approach was applied to identify and design novel peptide antigens that are specific to women with C. trachomatis-related infertility. The serological assay was developed such that it could potentially replace invasive techniques for early infertility investigation. The thesis further investigated the sero-prevalence of chlamydial infertility in women from a low-resource, high prevalence setting. In addition, the thesis also identified immune markers that were associated with the C. trachomatis-related infertility in women.
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| ID Code: | 94934 |
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| Item Type: | QUT Thesis (PhD) |
| Supervisor: | Huston, Willa, Timms, Peter, & Alexander, Kimberly |
| Keywords: | C. trachomatis, Female Infertility, Sequelae, Immunopathogenesis, Sero-epidemiology, Serological diagnosis, Cytokines, Samoa |
| Divisions: | Past > QUT Faculties & Divisions > Faculty of Health Past > Institutes > Institute of Health and Biomedical Innovation Current > Schools > School of Biomedical Sciences Current > Schools > School of Nursing |
| Institution: | Queensland University of Technology |
| Deposited On: | 28 Apr 2016 23:58 |
| Last Modified: | 08 Sep 2017 14:51 |
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