Changes in tissue diffusion and anisotropy following mechanical loading of ovine annulus fibrosus: A pilot study using magnetic resonance imaging

, , , & (2016) Changes in tissue diffusion and anisotropy following mechanical loading of ovine annulus fibrosus: A pilot study using magnetic resonance imaging. In 27th Annual Scientific Meeting of the Spine Society of Australia, 2016-04-08 - 2016-04-10. (Unpublished)

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The current pilot study sought to explore the functional micro-mechanics of the anulus fibrosus using both imaging and experimental methods, in order to better understand the underlying mechanisms which govern the interplay between disc mechanical function and microstructure. A comparison of DTI of anulus fibrosus samples before and after mechanical testing showed clear changes in diffusivity, indicating the tissue becomes more anisotropic following mechanical testing. This increase in anisotropy is possibly due to the collagen fibres becoming more aligned.

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ID Code: 97530
Item Type: Contribution to conference (Paper/Presentation)
Refereed: No
ORCID iD:
Little, J. Paigeorcid.org/0000-0001-8377-5343
Momot, Konstantin I.orcid.org/0000-0002-5695-153X
Pearcy, Mark J.orcid.org/0000-0002-1108-6503
Keywords: anulus fibrosis, collagen fibres, diffusion anisotropy, diffusion tensor imaging, disc microstructure, magnetic resonance imaging, ovine, vertebral disc, water diffusion
Pure ID: 57290040
Divisions: Past > Institutes > Institute of Health and Biomedical Innovation
Past > QUT Faculties & Divisions > Science & Engineering Faculty
Current > Research Centres > Australian Research Centre for Aerospace Automation
Copyright Owner: Copyright 2016 The Author(s)
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Deposited On: 19 Jul 2016 22:26
Last Modified: 09 Feb 2025 21:58