?url_ver=Z39.88-2004&rft_id=10.5204%2Fthesis.eprints.100030&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Manipulating+fibrin+structure+of+hematomas+enhances+large+bone+defects+healing&rft.creator=Wang%2C+Xin&rft.subject=Large+bone+defect&rft.subject=Hematoma&rft.subject=Fibrin+clot&rft.subject=Proinflammatory+cytokines&rft.subject=Structural+properties&rft.subject=ODTA&rft.description=Hematomas+(blood+clots)+are+known+important+factors+in+early+stages+of+fracture+repair.+This+project+characterized+the+differences+in+hematomas+between+normal+healing+and+delayed+healing+in+bone+defects.+It+was+found+that+manipulation+of+the+hematoma+structure+can+significantly+improve+bone+healing+and+result+in+significantly+increased+bone+formation.+This+project+will+lead+to+the+development+of+innovative+treatment+of+large+bone+defects%2C+fractures%2C+and+bone+non-union.&rft.publisher=Queensland+University+of+Technology&rft.date=2016&rft.type=Thesis&rft.format=application%2Fpdf&rft.relation=https%3A%2F%2Feprints.qut.edu.au%2F100030%2F1%2FXin_Wang_Thesis.pdf&rft.rights=free_to_read&rft.relation=doi%3A10.5204%2Fthesis.eprints.100030&rft.relation=Wang%2C+Xin+(2016)+Manipulating+fibrin+structure+of+hematomas+enhances+large+bone+defects+healing.+PhD+by+Publication%2C+Queensland+University+of+Technology.&rft.id_number=https%3A%2F%2Feprints.qut.edu.au%2F100030%2F&rft.identifier=Institute+of+Health+and+Biomedical+Innovation%3B+Science+%26+Engineering+Faculty%3B+School+of+Chemistry%2C+Physics+%26+Mechanical+Engineering