%0 Thesis %9 PhD %A Coulter, Sonali A. %D 2018 %F quteprints:116505 %K Antimicrobial Stewardship %K Cost-effectiveness %K Bloodstream infection %K Rapid Diagnostics %K Clinical Decision Support system %K Economic Evaluation %K MALDI-TOF %K Hospital %K Health Economics %K Health resource allocation %R 10.5204/thesis.eprints.116505 %T An economic evaluation of antimicrobial stewardship programs in metropolitan Australian hospitals %U https://eprints.qut.edu.au/116505/ %X This thesis provides the first economic evaluation of Antimicrobial Stewardship (AMS) interventions in two Metropolitan Australian Hospitals. AMS interventions are cost-saving from a hospital perspective and are cost-effective particularly if teamed with rapid diagnostics in the microbiology laboratory. The uncertainty in the mortality estimates does not allow for a high level of confidence in the cost-effectiveness decision for policy makers. While mortality is a useful metric, morbidity associated with bloodstream infections due to inappropriate prescribing needs to be collected over a longer period of time to capture the true benefits of AMS interventions.