?url_ver=Z39.88-2004&rft_id=10.5204%2Fthesis.eprints.243826&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Therapeutic+potential+of+boosting+NAD%2B+levels+in+aging+and+age-related+bone+loss&rft.creator=Sonar%2C+Yogita&rft.subject=NAD&rft.subject=NMN&rft.subject=Aging&rft.subject=NMNAT+1&rft.subject=Bone&rft.description=This+thesis+presents+a+study+exploring+the+use+of+Nicotinamide+Mononucleotide+(NMN)+to+boost+Nicotinamide+Adenine+Dinucleotide+(NAD)+levels+and+its+potential+in+combating+aging+and+age-related+bone+loss.+NAD%2C+a+vital+cellular+coenzyme%2C+regulates+DNA+repair+and+energy+production.+As+NAD+declines+with+age%2C+it+contributes+to+various+age-related+health+problems.+In+a+four-week+animal+model+study%2C+we+investigated+NMN+supplementation's+ability+to+raise+NAD+levels+and+its+implications+for+countering+age-related+bone+loss.+Our+results+offer+promising+insights+into+the+therapeutic+potential+of+NMN+for+addressing+NAD-related+aging+issues.&rft.publisher=Queensland+University+of+Technology&rft.date=2023-10-09&rft.type=Thesis&rft.format=application%2Fpdf&rft.relation=https%3A%2F%2Feprints.qut.edu.au%2F243826%2F1%2FYogita_Prashant_Sonar_Thesis.pdf&rft.rights=free_to_read&rft.rights=http%3A%2F%2Fcreativecommons.org%2Flicenses%2Fby-nc-nd%2F4.0%2F&rft.relation=doi%3A10.5204%2Fthesis.eprints.243826&rft.relation=Sonar%2C+Yogita+(2023)+Therapeutic+potential+of+boosting+NAD%2B+levels+in+aging+and+age-related+bone+loss.+Master+of+Philosophy+thesis%2C+Queensland+University+of+Technology.&rft.id_number=https%3A%2F%2Feprints.qut.edu.au%2F243826%2F&rft.identifier=Faculty+of+Engineering%3B+School+of+Mechanical%2C+Medical+%26+Process+Engineering