?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Development+of+a+novel+experimental+model+to+investigate+the+influence+of+mechanics+on+bone+healing&rft.creator=Tufekci%2C+Pelin+Melisa&rft.subject=Fracture+healing&rft.subject=Mechanobiology&rft.subject=Ovine+model&rft.subject=Mechanical+stimulation&rft.subject=External+stimulation&rft.subject=Interfragmentary+movement&rft.subject=Osteotomy&rft.subject=Animal+model&rft.description=This+dissertation+proposed+a+novel+experimental+model+combining+a+defect+configuration+with+an+active+instrumented+fixation+device+to+investigate+the+influence+of+mechanics+on+bone+healing.+The+proposed+defect+configuration+aimed+to+minimise+physiological+loading+within+an+experimental+fracture+gap+and+the+instrumented+fixator+was+used+for+the+application+of+controlled+displacements+and+in+vivo+stiffness+monitoring+of+the+healing+process.+This+thesis+has+provided+a+novel+approach+to+advance+current+knowledge+and+understanding+of+mechanobiology%2C+which+has+been+limited+in+previous+experimental+models.&rft.publisher=Queensland+University+of+Technology&rft.date=2015&rft.type=Thesis&rft.format=application%2Fpdf&rft.relation=https%3A%2F%2Feprints.qut.edu.au%2F90730%2F1%2FPelin_Tufekci_Thesis.pdf&rft.rights=free_to_read&rft.relation=Tufekci%2C+Pelin+Melisa+(2015)+Development+of+a+novel+experimental+model+to+investigate+the+influence+of+mechanics+on+bone+healing.+PhD+thesis%2C+Queensland+University+of+Technology.&rft.id_number=https%3A%2F%2Feprints.qut.edu.au%2F90730%2F&rft.identifier=Institute+of+Health+and+Biomedical+Innovation%3B+Science+%26+Engineering+Faculty%3B+School+of+Chemistry%2C+Physics+%26+Mechanical+Engineering