Browse By Person: McGovern, Jacqui

Hipwood, Luke, Dekker, Minne, Hutmacher, Dietmar W., Meinert, Christoph, & McGovern, Jacqui A. (2026) Photocrosslinkable lung dECM hydrogels promote stiffness-dependent lung cancer growth and chemoresistance. Materials Today Bio, 37, Article number: 102838.

Bhatia, Sugandha, Claxton, Briony, Thompson, Erik W, Lowe, Martin, Wagels, Michael, Nicholls, Wayne, Rowell, Philip, Hutmacher, Dietmar Werner, & McGovern, Jacqui Anne (2026) Patient-derived osteosarcoma tumoroid model reveals functional phenotypic diversity with implications for drug responses. Biofabrication, 18(1), Article number: 015036.

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Dekker, Minne, Hipwood, Luke, Ravichandran, Akhilandeshwari, Hutmacher, Dietmar W, Meinert, Christoph, & McGovern, Jacqui (2026) Bone-Derived dECM Hydrogels Support Tunable Microenvironments for In Vitro Osteogenic Differentiation. Advanced Healthcare Materials, 15(1), Article number: 2501350.

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Gospos, Jonathan, Laubach, Markus, Savi, Flavia Medeiros, Ravichandran, Akhilandeshwari, Bauer, Julian, Friedrich, Oliver, Holzapfel, Boris M., Wagner, Ferdinand, Mashimo, Tomoji, Saifzadeh, Siamak, Hutmacher, Dietmar W, & McGovern, Jacqui A (2025) Dynamic assessment of a humanized bone tumour microenvironment reveals insights into osteosarcoma primary tumour remodelling and lung metastases. Scientific Reports, 15(1), Article number: 45619.

Bessot, Agathe, Gunter, Jennifer, McGovern, Jacqui, & Bock, Nathalie (2025) Bone marrow adipocytes in cancer: Mechanisms, models, and therapeutic implications. Biomaterials, 322, Article number: 123341.

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Bhatia, Sugandha, Hipwood, Luke, Claxton, Briony, Bessot, Agathe, Weekes, Angus, Sokolowski, Kamil, Mashimo, Tomoji, Bock, Nathalie, & McGovern, Jacqui (2025) Divergent effects of premineralization and prevascularization on osteogenesis and vascular integration in humanized tissue engineered bone constructs. Acta Biomaterialia, 201, pp. 665-683.

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Bock, Nathalie, Delbianco, Martina, Eder, Michaela, Weinkamer, Richard, Amini, Shahrouz, Bidan, Cecile M., Cipitria, Amaia, Collin, Shaun P., Haupt, Larisa M., McGovern, Jacqui, Medeiros Savi, Flavia, Toh, Yi Chin, Hutmacher, Dietmar W., & Fratzl, Peter (2025) A materials science approach to extracellular matrices. Progress in Materials Science, 149, Article number: 101391.

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Bessot, Agathe, Medeiros Savi, Flavia, Gunter, Jennifer, Mendhi, Jayanti, Amini, Shahrouz, Waugh, David, McGovern, Jacqui, Hutmacher, Dietmar W., & Bock, Nathalie (2025) Humanized In Vivo Bone Tissue Engineering: In Vitro Preculture Conditions Control the Structural, Cellular, and Matrix Composition of Humanized Bone Organs. Advanced Healthcare Materials, 14(2), Article number: 2401939.

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Laubach, Markus, Bessot, Agathe, Saifzadeh, Siamak, Simon, Craig, Boecker, Wolfgang, Bock, Nathalie, Hutmacher, Dietmar W, & McGovern, Jacqui (2025) Assessing Cardiopulmonary Safety of Intramedullary Bone Graft Harvesting: A Comparative Study of the RIA 2 System and the ARA Concept. Journal of Orthopaedic Research, 43(5), pp. 984-993.

Bessot, Agathe, Rohl, Joan, Emmerich, Maria, Klotz, Anton, Ravichandran, Akhilandeshwari, Meinert, Christoph, Waugh, David, McGovern, Jacqui, Gunter, Jenni, & Bock, Nathalie (2025) ECM-mimicking hydrogel models of human adipose tissue identify deregulated lipid metabolism in the prostate cancer-adipocyte crosstalk under antiandrogen therapy. Materials Today Bio, 30, Article number: 101424.

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Frankenbach-Desor, Tina, Niesner, Isabella, Ahmed, Parveen, Dürr, Hans Roland, Klein, Alexander, Knosel, Thomas, Gospos, Jonathan, McGovern, Jacqui A, Hutmacher, Dietmar W, Holzapfel, Boris M, & Mayer-Wagner, Susanne (2025) Tissue-engineered patient-derived osteosarcoma models dissecting tumour-bone interactions. Cancer and Metastasis Reviews, 44(1), Article number: 8.

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Milton, Laura A., Davern, Jordan W., Hipwood, Luke, Chaves, Juliana D.S., McGovern, Jacqui, Broszczak, Daniel, Hutmacher, Dietmar W., Meinert, Christoph, & Toh, Yi Chin (2024) Liver click dECM hydrogels for engineering hepatic microenvironments. Acta Biomaterialia, 185, pp. 144-160.

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Laubach, Markus, Herath, Buddhi, Suresh, Sinduja, Saifzadeh, Siamak, Dargaville, Bronwin, Cometta Conde, Silvia, Schemenz, Victoria, Wille, Marie-Luise, Mcgovern, Jacqui, Hutmacher, Dietmar W, Medeiros Savi, Flavia, & Bock, Nathalie (2024) An innovative intramedullary bone graft harvesting concept as a fundamental component of scaffold-guided bone regeneration: A preclinical in vivo validation. Journal of Orthopaedic Translation, 47, pp. 1-14.

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Laubach, Markus, Bessot, Agathe, Saifzadeh, Siamak, Savi, Flavia Medeiros, Hildebrand, Frank, Bock, Nathalie, Hutmacher, Dietmar W, & McGovern, Jacqui (2024) In vivo study to assess fat embolism resulting from the Reamer-Irrigator-Aspirator 2 system compared to a novel aspirator-based concept for intramedullary bone graft harvesting. Archives of Orthopaedic and Trauma Surgery, 144(4), pp. 1535-1546.

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Laubach, Markus, Herath, Buddhi, Bock, Nathalie, Suresh, Sinduja, Saifzadeh, Siamak, Dargaville, Bronwin L., Mcgovern, Jacqui, Wille, Marie-Luise, Hutmacher, Dietmar W., & Medeiros Savi, Flavia (2023) In vivo characterization of 3D-printed polycaprolactone-hydroxyapatite scaffolds with Voronoi design to advance the concept of scaffold-guided bone regeneration. Frontiers in Bioengineering and Biotechnology, 11, Article number: 1272348.

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Laubach, Markus, Bessot, Agathe, McGovern, Jacqui, Saifzadeh, Siamak, Gospos, Jonathan, Segina, Daniel N, Kobbe, Philipp, Hildebrand, Frank, Wille, Marie-Luise, Bock, Nathalie, & Hutmacher, Dietmar W (2023) An in vivo study to investigate an original intramedullary bone graft harvesting technology. European Journal of Medical Research, 28(1), Article number: 349.

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Bessot, Agathe, Gunter, Jennifer, Waugh, David, Clements, Judith A, Hutmacher, Dietmar W, McGovern, Jacqui, & Bock, Nathalie (2023) GelMA and Biomimetic Culture Allow the Engineering of Mineralized, Adipose and Tumor Tissue Human Microenvironments for the Study of Advanced Prostate Cancer In Vitro and In Vivo. Advanced Healthcare Materials, 12(14), Article number: 2201701.

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Waugh, David J.J., McGovern, Jacqui A., & McCusker, Suzanne (2022) The challenges and emerging opportunities of targeting cytokines and chemokine-driven inflammatory signals in metastatic castrate-resistant prostate cancer. Critical Reviews in Oncogenesis, 27(1), pp. 25-43.

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Lahr, Christoph Alexander, Landgraf, Marietta, Wagner, Ferdinand, Cipitria, Amaia, Moreno- Jimenez, Ines, Bas, Onur, Schmutz, Beat, Meinert, Christoph, Dos Santos Cavalcanti, Amanda, Mashimo, Tomoji, Miyasaka, Yoshiki, Holzapfel, Boris, Shafiee, Abbas, Mcgovern, Jacqui, & Hutmacher, Dietmar (2022) A humanised rat model of osteosarcoma reveals ultrastructural differences between bone and mineralised tumour tissue. Bone, 158, Article number: 116018.

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Cheng, Matthew, Janzekovic, Jan, Mohseni, Mina, Medeiros Savi, Flavia, McGovern, Jacqui, Galloway, Graham, Wong, Clement, Saifzadeh, Siamak, Wagels, Michael, & Hutmacher, Dietmar W. (2021) A Preclinical Animal Model for the Study of Scaffold-Guided Breast Tissue Engineering. Tissue Engineering - Part C: Methods, 27(6), pp. 366-377.

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Iljas, J. D., Rohl, J., McGovern, J. A., Moromizato, K. H., Parker, T. J., & Cuttle, L. (2021) A human skin equivalent burn model to study the effect of a nanocrystalline silver dressing on wound healing. Burns, 47(2), pp. 417-429.

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McGovern, Jacqui A., Bock, Nathalie, Shafiee, Abbas, Martine, Laure C., Wagner, Ferdinand, Baldwin, Jeremy G., Landgraf, Marietta, Lahr, Christoph A., Meinert, Christoph, Williams, Elizabeth D., Pollock, Pamela M., Denham, Jim, Russell, Pamela J., Risbridger, Gail P., Clements, Judith A., Loessner, Daniela, Holzapfel, Boris M., & Hutmacher, Dietmar W. (2021) A humanized orthotopic tumor microenvironment alters the bone metastatic tropism of prostate cancer cells. Communications Biology, 4, Article number: 1014.

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Landgraf, Marietta, Lahr, Christoph A., Sanchez-Herrero, Alvaro, Meinert, Christoph, Shokoohmand, Ali, Pollock, Pamela M., Hutmacher, Dietmar W., Shafiee, Abbas, & McGovern, Jacqui A. (2020) Correction: Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of Zoledronic acid in vivo. Bone Research, 8, Article number: 17.

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Lahr, Christoph Alexander, Landgraf, Marietta, Sanchez Herrero, Alvaro, Dang, Hoang Phuc, Wagner, Ferdinand, Bas, Onur, Bray, Laura, Tran, Phong, Holzapfel, Boris, Shafiee, Abbas, Mcgovern, Jacqui, & Hutmacher, Dietmar (2020) A 3D-printed biomaterials-based platform to advance established therapy avenues against primary bone cancers. Acta Biomaterialia, 118, pp. 69-82.

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Moreno-Jimenez, I., Cipitria, A., Sanchez-Herrero, A., van Tol, A. F., Roschger, A., Lahr, C. A., McGovern, J. A., Hutmacher, D. W., & Fratzl, P. (2020) Human and mouse bones physiologically integrate in a humanized mouse model while maintaining species-specific ultrastructure. Science Advances, 6(44), Article number: abb9265.

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Sanchez-Herrero, Alvaro, Calvo, Isabel A., Flandes-Iparraguirre, Maria, Landgraf, Marietta, Lahr, Christoph A., Shafiee, Abbas, Granero-Molto, Froilán, Saez, Borja, Mazo, Manuel M., Paiva, Bruno, Pardo, Elena de Juan, Nicol, Andrew, Prosper, Felipe, Bray, Laura J., & McGovern, Jacqui A. (2020) Engineering a humanised niche to support human haematopoiesis in mice: Novel opportunities in modelling cancer. Cancers, 12(8), Article number: 2205.

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Landgraf, Marietta, Lahr, Christoph A., Kaur, Ishdeep, Shafiee, Abbas, Sanchez-Herrero, Alvaro, Janowicz, Phillip W., Ravichandran, Akhilandeshwari, Howard, Christopher B., Cifuentes-Rius, Anna, McGovern, Jacqui A., Voelcker, Nicolas H., & Hutmacher, Dietmar W. (2020) Targeted camptothecin delivery via silicon nanoparticles reduces breast cancer metastasis. Biomaterials, 240, Article number: 119791.

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Sparks, David S., Saifzadeh, Siamak, Savi, Flavia Medeiros, Dlaska, Constantin E., Berner, Arne, Henkel, Jan, Reichert, Johannes C., Wullschleger, Martin, Ren, Jiongyu, Cipitria, Amaia, McGovern, Jacqui A., Steck, Roland, Wagels, Michael, Woodruff, Maria Ann, Schuetz, Michael A., & Hutmacher, Dietmar W. (2020) A preclinical large-animal model for the assessment of critical-size load-bearing bone defect reconstruction. Nature Protocols, 15(3), pp. 877-924.

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Hwang, Ji Hui, Mcgovern, Jacqui, Minett, Geoffrey, Della Gatta, Paul, Roberts, Llion A., Harris, Jonathan, Thompson, Rik, Parker, Tony, Peake, Jonathan, & Neubauer, Oliver (2020) Mobilizing serum factors and immune cells through exercise to counteract age-related changes in cancer risk. Exercise Immunology Review, 26, pp. 80-99.

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Landgraf, Marietta, Lahr, Christoph A., Sanchez-Herrero, Alvaro, Meinert, Christoph, Shokoohmand, Ali, Pollock, Pamela M., Hutmacher, Dietmar W., Shafiee, Abbas, & McGovern, Jacqui A. (2019) Humanized bone facilitates prostate cancer metastasis and recapitulates therapeutic effects of zoledronic acid in vivo. Bone Research, 7, Article number: 31.

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Wagner, Ferdinand, Holzapfel, Boris, Martine, Laure, Mcgovern, Jacqui, Lahr, Christoph Alexander, Boxberg, Melanie, Prodinger, Peter Michael, Grassel, Susanne, Loessner, Daniela, & Hutmacher, Dietmar (2019) A humanized bone microenvironment uncovers HIF2 alpha as a latent marker for osteosarcoma. Acta Biomaterialia, 89, pp. 372-381.

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Evans, Jemma, Infusini, Giuseppe, McGovern, Jacqui, Cuttle, Leila, Webb, Andrew, Nebl, Thomas, Milla, Liz, Kimble, Roy, Kempf, Margit, Andrews, Christine, Leavesley, David, & Salamonsen, Lois (2019) Menstrual fluid factors facilitate tissue repair: identification and functional action in endometrial and skin repair. FASEB Journal, 33(1), pp. 584-605.

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Mcgovern, Jacqui, Griffin, Michelle, & Hutmacher, Dietmar (2018) Animal models for bone tissue engineering and modelling disease. DMM Disease Models and Mechanisms, 11(4), Article number: 33084 1-14.

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Wagner, Ferdinand, Holzapfel, Boris, McGovern, Jacqui, Shafiee, Abbas, Baldwin, Jeremy, Martine, Laure, Lahr, Christoph Alexander, Wunner, Felix, Friis, Thor, Bas, Onur, Boxberg, Melanie, Prodinger, Peter Michael, Shokoohmand, Ali, Moi, Davide, Mazzieri, Roberta, Loessner, Daniela, & Hutmacher, Dietmar (2018) Humanization of bone and bone marrow in an orthotopic site reveals new potential therapeutic targets in osteosarcoma. Biomaterials, 171, pp. 230-246.

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McGovern, Jacqui, Shafiee, Abbas, Wagner, Ferdinand, Lahr, Christoph Alexander, Landgraf, Marietta, Meinert, Christoph, Williams, Elizabeth, Russell, Pamela, Clements, Judith, Loessner, Daniela, Holzapfel, Boris, Risbridger, Gail, & Hutmacher, Dietmar (2018) Humanization of the prostate microenvironment reduces homing of PC3 prostate cancer cells to human tissue-engineered bone. Cancers, 10(11), Article number: 438 1-15.

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Shafiee, Abbas, McGovern, Jacqui, Lahr, Christoph Alexander, Meinert, Christoph, Moi, Davide, Wagner, Ferdinand, Landgraf, Marietta, Juan Pardo, Elena, Mazzieri, Roberta, & Hutmacher, Dietmar (2018) Immune system augmentation via humanization using stem/progenitor cells and bioengineering in a breast cancer model study. International Journal of Cancer, 143(6), pp. 1470-1482.

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Poh, Su Ping Patrina, Schmauss, Verena, Mcgovern, Jacqui, Schmauss, Daniel, Chhaya, Mohit, Foehr, Peter, Seeger, Markus, Ntziachristos, Vasilis, Hutmacher, Dietmar, Griensven, Martijn, Schantz, Jan-Thorsten, & Balmayor, Elizabeth (2018) Non-linear optical microscopy and histological analysis of collagen, elastin and lysyl oxidase expression in breast capsular contracture. European Journal of Medical Research, 23(1), Article number: 30.

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